Whether you’re a seasoned player or new to PrizePicks, having a strategic approach is essential for maximizing your entries. NFL Week 16 brings plenty of opportunities to capitalize on player props, and this cheat sheet will help you make smart picks and avoid common pitfalls.
PrizePicks Building Blocks for NFL Week 16
- Lamar Jackson: 1+ Passing TD | Hit 20/20
- Jayden Daniels: 175+ Passing Yds | Hit 13/13
- Derrick Henry: 60+ Rushing Yds | Hit 13/13
- Kyren Williams: 60+ Rushing Yds | Hit 12/12
- Sam Darnold: 200+ Passing Yds | Hit 9/9
- Saquon Barkley: 60+ Rushing Yds | Hit 9/9
- DeAndre Hopkins: 25+ Receiving Yds | Hit 8/8
- Jaxon Smith-Njigba: 50+ Receiving Yds | Hit 7/7
- Jerry Jeudy: 50+ Receiving Yds | Hit 7/7
- Jonnu Smith: 40+ Receiving Yds | Hit 7/7
- Davante Adams: 5+ Receptions | Hit 6/6
- Jordan Addison: 3+ Receptions | Hit 5/5
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|---|---|---|
| Underdog Fantasy | $1,000 DEPOSIT BONUS | MHS3P |
| Sleeper Fantasy | PLAY $5, GET $55 FREE | MHS3P |
| PrizePicks | FREE $50 BONUS | MHS3P |
| Boom Fantasy | RISK-FREE $100 ENTRY | MHS3P |
This Week’s Top NFL Player Trends (Week 16)
NFL Player Streaks with 100% Hit Rates 🔥
- Joe Burrow: 250+ Passing Yds | 100% | CLE @ CIN
- Kyler Murray: Over 223.5 Passing Yds | 100% | ARI @ CAR
- Sam Darnold: 225+ Passing Yds | 100% | MIN @ SEA
- Kyren Williams: 70+ Rushing Yds | 100% | LAR @ NYJ
- DeAndre Hopkins: 3+ Receptions | 100% | TEN @ IND
- Jerry Jeudy: Over 4.5 Receptions | 100% | CLE @ CIN
- Chase Brown: 3+ Receptions | 100% | CLE @ CIN
- Sam LaPorta: 3+ Receptions | 100% | DET @ CHI
- Jameson Williams: 3+ Receptions | 100% | DET @ CHI
- Josh Downs: 3+ Receptions | 100% | TEN @ IND
- Noah Fant: Over 2.5 Receptions | 100% | MIN @ SEA
- Khalil Shakir: 4+ Receptions | 100% | NWE @ BUF
- Trey McBride: 60+ Receiving Yds | 100% | ARI @ CAR
- Adam Thielen: 40+ Receiving Yds | 100% | ARI @ CAR
- Drake London: 50+ Receiving Yds | 100% | NYG @ ATL
- Jaxon Smith-Njigba: Over 62.5 Receiving Yds | 100% | MIN @ SEA
- Jordan Addison: Over 51.5 Receiving Yds | 100% | MIN @ SEA
- Jonnu Smith: 25+ Receiving Yds | 100% | SFO @ MIA
PrizePicks NFL Week 16 Line Movement
| Player | Team | Opp | Date & Time | Market | Previous Line | PrizePicks | Change | % Change |
| Aaron Jones | MIN | @SEA | Sun Dec 22 4:05 pm | Rushing + Receiving Yards | 87.5 | 83.5 | -4.0 | 4.6% |
| Tyler Lockett | SEA | MIN | Sun Dec 22 4:05 pm | Receiving Yards | 19.5 | 20.5 | 1.0 | 5.1% |
| Noah Fant | SEA | MIN | Sun Dec 22 4:05 pm | Receiving Yards | 24.5 | 23.5 | -1.0 | 4.1% |
| DK Metcalf | SEA | MIN | Sun Dec 22 4:05 pm | Receiving Yards | 56.5 | 59.5 | 3.0 | 5.3% |
| Jaxon Smith-Njigba | SEA | MIN | Sun Dec 22 4:05 pm | Receiving Yards | 61.5 | 60.5 | -1.0 | 1.6% |
| Rhamondre Stevenson | NE | @BUF | Sun Dec 22 4:25 pm | Rushing + Receiving Yards | 64.5 | 66.5 | 2.0 | 3.1% |
| Mike Gesicki | CIN | CLE | Sun Dec 22 1:00 pm | Receiving Yards | 25.5 | 27.5 | 2.0 | 7.8% |
| Jerome Ford | CLE | @CIN | Sun Dec 22 1:00 pm | Rushing + Receiving Yards | 72.5 | 74.5 | 2.0 | 2.8% |
| Wan’Dale Robinson | NYG | @ATL | Sun Dec 22 1:00 pm | Receiving Yards | 35.5 | 34.5 | -1.0 | 2.8% |
| De’Von Achane | MIA | SF | Sun Dec 22 4:25 pm | Receiving Yards | 38.5 | 36.5 | -2.0 | 5.2% |
| Breece Hall | NYJ | LAR | Sun Dec 22 1:00 pm | Rushing Yards | 55.5 | 54.5 | -1.0 | 1.8% |
| Jerry Jeudy | CLE | @CIN | Sun Dec 22 1:00 pm | Receiving Yards | 60.5 | 62.5 | 2.0 | 3.3% |
| Breece Hall | NYJ | LAR | Sun Dec 22 1:00 pm | Rush Attempts | 13.5 | 13.0 | -0.5 | 3.7% |
| Sam Darnold | MIN | @SEA | Sun Dec 22 4:05 pm | Passing Yards | 242.5 | 243.5 | 1.0 | 0.4% |
| Chuba Hubbard | CAR | ARI | Sun Dec 22 1:00 pm | Rushing + Receiving Yards | 89.5 | 92.5 | 3.0 | 3.4% |
| Josh Allen | BUF | @NE | Sun Dec 22 4:25 pm | Passing Yards | 236.5 | 234.5 | -2.0 | 0.8% |
| DeMario Douglas | NE | @BUF | Sun Dec 22 4:25 pm | Receiving Yards | 35.5 | 36.5 | 1.0 | 2.8% |
| Joe Burrow | CIN | CLE | Sun Dec 22 1:00 pm | Pass Completions | 24.5 | 24.0 | -0.5 | 2.0% |
| Lamar Jackson | BAL | PIT | Tomorrow 4:30 pm | Passing Yards | 227.5 | 226.5 | -1.0 | 0.4% |
Key Tips for Building Your Entries
- Understand Game Scripts
Consider how games are likely to play out. Will it be a high-scoring shootout or a defensive slugfest? Game scripts influence player performance, so align your picks with expected outcomes. - Look for Consistent Performers
Focus on players who have consistently hit their projected stats this season. This reduces risk and provides a reliable foundation for your picks. - Use Recent Player Trends
Analyze the last few weeks of data. Is a quarterback heating up? Is a running back facing a favorable defensive matchup? Tracking trends can help you spot value in player projections. - Diversify Your Picks
Avoid putting all your eggs in one basket. Spread your picks across multiple games and player types (passing, rushing, receiving, etc.) to mitigate risk. - Leverage Injury Reports
Late-breaking injury news can dramatically alter player projections. If a star player is ruled out, their backup often becomes a strong value play.
Common Mistakes to Avoid
- Overloading on Stars: Big names don’t always meet projections, especially against tough defenses.
- Ignoring Weather: Rain, snow, or high winds can heavily impact passing and kicking props.
- Chasing Big Cards: Stick to manageable entries like 2 or 3 player for a higher chance of success.
