Whether you’re a seasoned PrizePicks player or brand new to the platform, having a smart strategy is essential for maximizing your entries. Our PrizePicks Week 3 NFL cheat sheet breaks down the top player props, highlights the best opportunities on the board, and helps you avoid common mistakes. With so many matchups to kick off the season, this guide will put you in the best position to make confident picks right from the start.
PrizePicks Building Blocks for NFL Week 3
NFL Week 3 – 100% Anytime TD Streaks
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Josh Jacobs (GB): 11/11
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Jalen Hurts (PHI): 5/5
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Deebo Samuel (WSH): 4/4
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James Cook (BUF): 3/3
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DeAndre Hopkins (BAL): 3/3
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De’Von Achane (MIA): 3/3
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Saquon Barkley (PHI): 2/2
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J.K. Dobbins (DEN): 2/2
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Keenan Allen (LAC): 2/2
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Tucker Kraft (GB): 2/2
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Quentin Johnston (LAC): 2/2
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Patrick Mahomes (KC): 2/2
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PrizePicks NFL Week 3 Line Movement
*Updated 9/21/25
| Player | Team | Opp | Date | Market | Prev. Line | PrizePicks | Change | %Change |
| Kenneth Walker | SEA | NO | Tomorrow 2:05 pm | Rushing Yards | 67.5 | 78.5 | 11 | 16.3% |
| Rashid Shaheed | NO | @SEA | Tomorrow 2:05 pm | Receiving Yards | 37.5 | 45.5 | 8 | 21.3% |
| Josh Jacobs | GB | @CLE | Tomorrow 11:00 am | Rushing + Receiving Yards | 83.5 | 90.5 | 7 | 8.4% |
| Chris Olave | NO | @SEA | Tomorrow 2:05 pm | Receiving Yards | 51.5 | 58.5 | 7 | 13.6% |
| Kyler Murray | ARI | @SF | Tomorrow 2:25 pm | Passing Yards | 210.5 | 217.5 | 7 | 3.3% |
| Ashton Jeanty | LV | @WAS | Tomorrow 11:00 am | Rushing + Receiving Yards | 71.5 | 77.5 | 6 | 8.4% |
| Josh Downs | IND | @TEN | Tomorrow 11:00 am | Receiving Yards | 34.5 | 40.5 | 6 | 17.4% |
| Geno Smith | LV | @WAS | Tomorrow 11:00 am | Passing + Rushing Yards | 250.5 | 256.5 | 6 | 2.4% |
| Justin Herbert | LAC | DEN | Tomorrow 2:05 pm | Passing Yards | 245.5 | 251.5 | 6 | 2.4% |
| Terry McLaurin | WAS | LV | Tomorrow 11:00 am | Receiving Yards | 40.5 | 45.5 | 5 | 12.3% |
| Jaylen Warren | PIT | @NE | Tomorrow 11:00 am | Rushing Yards | 53.5 | 58.5 | 5 | 9.3% |
| Wan’Dale Robinson | NYG | KC | Tomorrow 6:20 pm | Receiving Yards | 38.5 | 43.5 | 5 | 13.0% |
| Javonte Williams | DAL | @CHI | Tomorrow 2:25 pm | Rushing + Receiving Yards | 81.5 | 86.5 | 5 | 6.1% |
| Russell Wilson | NYG | KC | Tomorrow 6:20 pm | Passing Yards | 217.5 | 222.5 | 5 | 2.3% |
| Sterling Shepard | TB | NYJ | Tomorrow 11:00 am | Receiving Yards | 20.5 | 25.5 | 5 | 24.4% |
| Hollywood Brown | KC | @NYG | Tomorrow 6:20 pm | Receiving Yards | 49.5 | 54.5 | 5 | 10.1% |
| Sam Darnold | SEA | NO | Tomorrow 2:05 pm | Passing + Rushing Yards | 225.5 | 230.5 | 5 | 2.2% |
| Bucky Irving | TB | NYJ | Tomorrow 11:00 am | Receiving Yards | 17.5 | 22.5 | 5 | 28.6% |
| Cam Skattebo | NYG | KC | Tomorrow 6:20 pm | Rushing + Receiving Yards | 46.5 | 51.5 | 5 | 10.8% |
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This Week’s Top NFL Player Trends (Week 3)
🏈 NFL Week 3 – 100% QB Alternate Lines
1️⃣ B. Young: 1+ Pass TD – 12/12 Games
2️⃣ J. Flacco: 175+ Pass Yds – 8/8 Games
3️⃣ J. Goff: 225+ Pass Yds – 8/8 Games
4️⃣ B. Nix: 15+ Rush Yds – 7/7 Games
5️⃣ J. Herbert: 225+ Pass Yds – 6/6 Games
6️⃣ L. Jackson: 175+ Pass Yds – 5/5 Games
7️⃣ M. Stafford: 200+ Pass Yds – 4/4 Games
8️⃣ C. Stroud: 15+ Rush Yds – 4/4 Games
9️⃣ B. Mayfield: 20+ Rush Yds – 4/4 Games
🔟 G. Smith: 10+ Rush Yds – 4/4 Games
Key Tips for Building Your Entries
- Understand Game Scripts
Consider how games are likely to play out. Will it be a high-scoring shootout or a defensive slugfest? Game scripts influence player performance, so align your picks with expected outcomes. - Look for Consistent Performers
Focus on players who have consistently hit their projected stats this season. This reduces risk and provides a reliable foundation for your picks. - Use Recent Player Trends
Analyze the last few weeks of data. Is a quarterback heating up? Is a running back facing a favorable defensive matchup? Tracking trends can help you spot value in player projections. - Diversify Your Picks
Avoid putting all your eggs in one basket. Spread your picks across multiple games and player types (passing, rushing, receiving, etc.) to mitigate risk. - Leverage Injury Reports
Late-breaking injury news can dramatically alter player projections. If a star player is ruled out, their backup often becomes a strong value play.
Common Mistakes to Avoid
- Overloading on Stars: Big names don’t always meet projections, especially against tough defenses.
- Ignoring Weather: Rain, snow, or high winds can heavily impact passing and kicking props.
- Chasing Big Cards: Stick to manageable entries like 2 or 3 player for a higher chance of success.
