Whether you’re a seasoned PrizePicks player or brand new to the platform, having a smart strategy is essential for maximizing your entries. Our PrizePicks Week 1 NFL cheat sheet breaks down the top player props, highlights the best opportunities on the board, and helps you avoid common mistakes. With so many matchups to kick off the season, this guide will put you in the best position to make confident picks right from the start.
PrizePicks Building Blocks for NFL Week 1
Chiefs vs. Chargers Friday ALT Line Trends
Chargers
- Ladd McConkey: 50+ Rec Yds ✅ 11/11
- Justin Herbert: 175+ Pass Yds ✅ 6/6
- Will Dissly: 10+ Rec Yds ✅ 4/4
Chiefs
- Xavier Worthy: 40+ Rec Yds ✅ 10/10
- Patrick Mahomes: 10+ Rush Yds ✅ 7/7
- Patrick Mahomes: 175+ Pass Yds ✅ 5/5
- Kareem Hunt: 1+ Reception ✅ 6/6
- JuJu Smith-Schuster: 15+ Rec Yds ✅ 2/2
This Week’s Top NFL Player Trends (Week 1)
Wide Receiver Prop Streaks
🔥 100% hit rates
K. Allen: 25+ Yds ➡️ 13/13
C. Ridley: 40+ Yds ➡️ 12/12
A. St. Brown: 5+ Catches ➡️ 11/11
L. McConkey: 50+ Yds ➡️ 11/11
P. Nacua: 5+ Catches ➡️ 10/10
X. Worthy: 40+ Yds ➡️ 10/10
M. Nabers: 50+ Yds ➡️ 10/10
J. Chase: 6+ Catches ➡️ 10/10
A. Thielen: 20+ Yds ➡️ 10/10
D. Adams: 4+ Catches ➡️ 10/10
💪 Quarterback Streaks
🔥 100% hit rates
J. Goff: 200+ Yds ➡️ 10/10
J. Burrow: 250+ Yds ➡️ 9/9
K. Murray: 200+ Yds ➡️ 8/8
B. Nix: 20+ Rush Yds ➡️ 5/5
G. Smith: 5+ Rush Yds ➡️ 4/4
J. Herbert: 225+ Yds ➡️ 4/4
J. Daniels: 200+ Yds ➡️ 3/3
J. Allen: 30+ Rush Yds ➡️ 3/3
J. Flacco: 200+ Yds ➡️ 3/3
S. Rattler: 150+ Yds ➡️ 3/3
🏈 NFL Week 1 – 100% TD Streaks
J. Jacobs: Anytime TD ✅ 9/9
J. Gibbs: Anytime TD ✅ 6/6
D. Henry: Anytime TD ✅ 4/4
T. McLaurin: Anytime TD ✅ 4/4
J. Hurts: Anytime TD ✅ 3/3
B. Robinson: Anytime TD ✅ 3/3
J. Taylor: Anytime TD ✅ 3/3
A. Brown: Anytime TD ✅ 2/2
A. Jones: Anytime TD ✅ 2/2 vs CHI
J. Chase: Anytime TD ✅ 2/2 vs CLE
(Data from CLEATZ.com)
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PrizePicks NFL Week 1 Line Movement
| Player | Team | Opp | Date | Market | Prev. Line | PrizePicks | Change |
| Jonathan Taylor | IND | MIA | Sun Sep 7 11:00 am | Rushing Yards | 79.5 | 76.5 | -3 |
| Andrei Iosivas | CIN | @CLE | Sun Sep 7 11:00 am | Receiving Yards | 21.5 | 20.5 | -1 |
| Tee Higgins | CIN | @CLE | Sun Sep 7 11:00 am | Receiving Yards | 63.5 | 62.5 | -1 |
| Chase Brown | CIN | @CLE | Sun Sep 7 11:00 am | Rushing Yards | 65.5 | 66.5 | 1 |
| Rhamondre Stevenson | NE | LV | Sun Sep 7 11:00 am | Rushing Yards | 42.5 | 43.5 | 1 |
| Michael Wilson | ARI | @NO | Sun Sep 7 11:00 am | Receiving Yards | 24.5 | 25.5 | 1 |
| Ja’Marr Chase | CIN | @CLE | Sun Sep 7 11:00 am | Receiving Yards | 85.5 | 86.5 | 1 |
| Jakobi Meyers | LV | @NE | Sun Sep 7 11:00 am | Receiving Yards | 51.5 | 52.5 | 1 |
| Brian Thomas | JAX | CAR | Sun Sep 7 11:00 am | Receiving Yards | 76.5 | 73.5 | -3 |
| Brenton Strange | JAX | CAR | Sun Sep 7 11:00 am | Receiving Yards | 28.5 | 29.5 | 1 |
| Jaylin Noel | HOU | @LAR | Sun Sep 7 2:25 pm | Receiving Yards | 21.5 | 17.5 | -4 |
| Derrick Henry | BAL | @BUF | Sun Sep 7 6:20 pm | Rushing + Receiving Yards | 89.5 | 88.5 | -1 |
| Michael Pittman | IND | MIA | Sun Sep 7 11:00 am | Receiving Yards | 46.5 | 44.5 | -2 |
| James Cook | BUF | BAL | Sun Sep 7 6:20 pm | Rushing + Receiving Yards | 69.5 | 68.5 | -1 |
| Trey McBride | ARI | @NO | Sun Sep 7 11:00 am | Receiving Yards | 62.5 | 63.5 | 1 |
| James Cook | BUF | BAL | Sun Sep 7 6:20 pm | Receiving Yards | 11.5 | 10.5 | -1 |
| DeAndre Hopkins | BAL | @BUF | Sun Sep 7 6:20 pm | Receiving Yards | 13.5 | 14.5 | 1 |
| Keon Coleman | BUF | BAL | Sun Sep 7 6:20 pm | Receiving Yards | 33.5 | 36.5 | 3 |
| Spencer Rattler | NO | ARI | Sun Sep 7 11:00 am | Passing Yards | 199.5 | 195.5 | -4 |
Key Tips for Building Your Entries
- Understand Game Scripts
Consider how games are likely to play out. Will it be a high-scoring shootout or a defensive slugfest? Game scripts influence player performance, so align your picks with expected outcomes. - Look for Consistent Performers
Focus on players who have consistently hit their projected stats this season. This reduces risk and provides a reliable foundation for your picks. - Use Recent Player Trends
Analyze the last few weeks of data. Is a quarterback heating up? Is a running back facing a favorable defensive matchup? Tracking trends can help you spot value in player projections. - Diversify Your Picks
Avoid putting all your eggs in one basket. Spread your picks across multiple games and player types (passing, rushing, receiving, etc.) to mitigate risk. - Leverage Injury Reports
Late-breaking injury news can dramatically alter player projections. If a star player is ruled out, their backup often becomes a strong value play.
Common Mistakes to Avoid
- Overloading on Stars: Big names don’t always meet projections, especially against tough defenses.
- Ignoring Weather: Rain, snow, or high winds can heavily impact passing and kicking props.
- Chasing Big Cards: Stick to manageable entries like 2 or 3 player for a higher chance of success.