No. 1 – Brock Osweiler

He’s waited three-and-a-half years for this opportunity, biding his time on the bench behind a quarterback who never misses a game and won’t surrender a single snap to his backup. But finally, the Broncos second-round pick in 2012 gets his chance to run the show, as Osweiler gets the starting nod in Chicago. And there’s a lot at stake. For one, he needs to help end the Broncos two-game losing streak, before a once-promising season careens off course. For two, he’s playing for his next contract, as Osweiler will be a free agent at year’s end; if he plays well, someone (probably Denver) will give him big money to be their QB in 2016. And he’s playing for John Elway’s reputation. Not only did the Duke of Denver draft him, but this week also features a showdown with the head coach No. 7 fired; beating John Fox is hugely important.